Automatic Extraction of DNA Profiles in Polyacrilamide Gel Electrophoresis Images

In this paper is presented a method for the automatic DNA spots classification and extraction of profiles associated in DNA polyacrilamide gel electrophoresis based on image processing. A software which implements this method was developed, composed by four modules: Digital image acquisition, image preprocessing, feature extraction and classification, and DNA profile extraction. The use of different types of algorithms as: C4.5 Decision Trees, Support Vector Machines and Leader Algorithm are needed to resolve all the tasks. The experimental results show that this method has a very nice computational behavior and effectiveness, and provide a very useful tool to decrease the time and increase the quality of the specialist responses.